Range of adiposity and cardiorenal syndrome

Cardiorenal syndrome.

Very often, physicians confront with patients who have concomitant heart and kidney failure. The coexistence of kidney and heart failure carries an extremely bad prognosis. The exact cause of deterioration of kidney function and the mechanism underlying this interaction are complex, multifactorial in nature, and still not completely understood. Both the heart and the kidney act in tandem to reg...

Cardiorenal syndrome

Kidney dysfunction in patients with heart failure and cardiovascular disorders in patients with chronic kidney disease are common. A recently proposed consensus definition of cardiorenal syndrome stresses the bidirectional nature of these heart-kidney interactions. The treatment of cardiorenal syndrome is challenging, however, promising new therapeutic options are currently being investigated i...

Origins of Cardiorenal Syndrome and the Cardiorenal Connection

Nitric oxide mediated the effects of nebivolol in cardiorenal syndrome

Objective(s): Despite several proposed mechanisms for the pathophysiology of cardiorenal syndrome (CRS), the exact mechanism remains unclear. Nitrosative stress has been argued as a key mechanism recently. Nebivolol is a beta-blocker with nitric oxide (NO)-releasing effect. In the present study, NO-mediated effects of two different treatment regimes of nebivolol in CRS...

Cardiorenal syndrome: introduction.

Introduction One hundred years ago, in November of 1913, Thomas Lewis from University College Hospital, London, delivered a lecture entitled “Paroxysmal Dyspnoea in Cardio–Renal Patients,” in which he provided his clinical observations on a number of patients with dyspnea related to advanced heart and kidney disease, referred to as cardiac and uraemic asthma respectively, and expounded his theo...